Mouse monoclonal-Anti- Caspase 8 (CASP8)-20ug
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Catalog number
MAA853Bo21-20ug
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Price
Please ask
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Size
20ug
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Organism Species
Bos taurus; Bovine (Cattle)
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Source
Monoclonal antibody preparation
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Purification
Protein A + Protein G affinity chromatography
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Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
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Item Name
Caspase 8
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Immunogen
RPA853Bo01-Recombinant Caspase 8 (CASP8)
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Image number
1
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Species reactivity
Bovine
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Sequence of immunogen
Leu25~Ile175
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Aplication
WB
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Clonality
Mouse monoclonal
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Concentration
1mg/ml
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Alternative Names
CAP4; FLICE; MACH; MCH5; Cysteinyl Aspartate Specific Proteinases 8; Apoptotic cysteine protease; FADD-homologous ICE/ced-3-like protease; MORT1-associated ced-3 homolog
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Applicable Secondary Antibody
SAA544Mu08, SAA544Mu09, SAA544Mu07, SAA544Mu19, SAA544Mu18, SAA544Mu17
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Delivery condition
4℃ with ice bags
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Storage instructions
Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
CASP8
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Short name
Mouse monoclonal-Anti- Caspase 8 (CASP8)-20ug
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Technique
Mouse monoclonal, Mouse, anti, antibody to, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Species
Mouse, Mouses
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Alternative name
Mouse monoclonal-antibody to- caspase 8 (caspase 8, apoptosis-related cysteine peptidase)-20ug
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Alternative technique
murine, antibodies
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Alternative to gene target
caspase 8, apoptosis-related cysteine peptidase, ALPS2B and CAP4 and Casp-8 and FLICE and MACH and MCH5, CASP8 and IDBG-78534 and ENSG00000064012 and 841, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, nuclei, Casp8 and IDBG-157464 and ENSMUSG00000026029 and 12370, CASP8 and IDBG-643207 and ENSBTAG00000015718 and 507481
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Gene info
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Identity
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Gene
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Long gene name
caspase 8
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Synonyms gene name
- caspase 8, apoptosis-related cysteine protease
- caspase 8, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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