Rat Anti-Mouse CD2/LFA-2-LE/AF

• Catalog number
  GEN673127
• Price
  Please ask
• Size
  500ug

• Also known as
  CD2 (LFA-2)
• Other names
  CD2 antigen; T-cell surface antigen CD2; T-cell surface antigen CD2; LFA-3 receptor; lymphocyte antigen 37; T-cell surface antigen T11/Leu-5; CD2 antigen; LFA-2; LFA-3 receptor; Lymphocyte antigen 37; Ly-37; T-cell surface antigen T11/Leu-5
• Category
  Secondary Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Cd2; Cd2; Ly37; LFA-2; Ly-37; Ly-37
• Gene name synonims
  Cd2; Cd2; Ly37; LFA-2; Ly-37; Ly-37
• Other gene names
  Cd2; Cd2; Ly37; LFA-2; Ly-37; Ly-37
• Clonality
  Monoclonal
• Immunoglobulin isotype
  Rat IgG1 kappa
• Clone
  42353
• Host organism
  Rat (Rattus norvegicus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Mouse CD2/LFA-2 (Mr 45-58 kDa) CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules.^1 It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. ^1-3 In the mouse, CD2 is the receptor for CD48.^4 CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, Tcell signaling and intrathymic differentiation.^5-10; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Low Endotoxin, Azide - Free (LE/AF)
• Concentration
  N/A
• Storage and shipping
  The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg or 0.1 mg in 1.0 mL of PBS/NaN3. Store at 2- 8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below Store the antibody at -20 degrees Celsius.. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product the antibody should be stored at -20 degrees Celsius. immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
• Tested applications
  Flow Cytometry; Immunoprecipitation
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

• Gene target
  CD2/LFA-2-LE/AF  
• Gene symbol
  CD2, FUT3, HPS4, ITGAL, NPAS4, ITGB2, MIR1289-2, MIR521-2, MIR509-2, MIR512-2
• Short name
  Anti-Mouse CD2/LFA-2-LE/AF
• Technique
  anti-, Mouse, anti, antibody to, antibodies, mouses
• Host
  Rat
• Species
  Mouse, Mouses, Rats
• Alternative name
  Anti-Rat Anti-Mouse CD2/LFA-2-LE/AF
• Alternative technique
  murine, antibodies
• Alternative to gene target
  CD2 molecule, LFA-2 and SRBC and T11, CD2 and IDBG-101417 and ENSG00000116824 and 914, protein homodimerization activity, Extracellular, Cd2 and IDBG-179684 and ENSMUSG00000027863 and 12481, CD2 and IDBG-634458 and ENSBTAG00000017256 and 497022

Gene info

• Identity
  HGNC:1639
• Gene
  CD2
• Long gene name
  CD2 molecule
• Synonyms gene
  • SRBC
• Synonyms gene name
  • CD2 antigen (p50), sheep red blood cell receptor
• GenBank acession
  • BC033583
• Locus
  1p13.1
• Discovery year
  1986-01-01
• Entrez gene record
  914
• Pubmed identfication
  • 2437578
• RefSeq identity
  • NM_001767
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000022750

Gene info

• Identity
  HGNC:4014
• Gene
  FUT3
• Long gene name
  fucosyltransferase 3 (Lewis blood group)
• Synonyms gene
  • LE
• Synonyms gene name
  • fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included)
• Synonyms
  • CD174
• Synonyms name
  • galactoside 3(4)-L-fucosyltransferase
• Locus
  19p13.3
• Discovery year
  1993-04-08
• Entrez gene record
  2525
• Pubmed identfication
  • 1977660
  • 1740457
• RefSeq identity
  • NM_000149
• Classification
  • Fucosyltransferases
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000180614
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • LRG_800

Gene info

• Identity
  HGNC:15844
• Gene
  HPS4
• Long gene name
  HPS4 biogenesis of lysosomal organelles complex 3 subunit 2
• Synonyms gene name
  • Hermansky-Pudlak syndrome 4
• Synonyms
  • KIAA1667
  • LE
  • BLOC3S2
• Locus
  22q12.1
• Discovery year
  2001-06-28
• Entrez gene record
  89781
• Pubmed identfication
  • 11836498
  • 12663659
• RefSeq identity
  • NM_022081
• Classification
  • Biogenesis of lysosomal organelles complex 3
• VEGA ID
  OTTHUMG00000030459
• Locus Specific Databases
  • Mutations of the Human light ear Gene (le, HPS4)
  • LRG_590

Gene info

• Identity
  HGNC:6148
• Gene
  ITGAL
• Long gene name
  integrin subunit alpha L
• Synonyms gene
  • CD11A
• Synonyms gene name
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
• Synonyms
  • LFA-1
  • LFA1A
• Synonyms name
  • antigen CD11A (p180)
  • lymphocyte function-associated antigen 1, alpha polypeptide
• Locus
  16p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  3683
• Pubmed identfication
  • 3284962
• Classification
  • Integrin alpha subunits
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000176964

Gene info

• Identity
  HGNC:18983
• Gene
  NPAS4
• Long gene name
  neuronal PAS domain protein 4
• Synonyms
  • PASD10
  • NXF
  • Le-PAS
  • bHLHe79
• GenBank acession
  • AB049469
• Locus
  11q13.2
• Discovery year
  2005-09-26
• Entrez gene record
  266743
• Pubmed identfication
  • 14701734
• RefSeq identity
  • NM_178864
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000167045

Gene info

• Identity
  HGNC:6155
• Gene
  ITGB2
• Long gene name
  integrin subunit beta 2
• Synonyms gene
  • CD18
  • MFI7
• Synonyms gene name
  • integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
• Synonyms
  • LFA-1
  • MAC-1
• Synonyms name
  • complement component 3 receptor 3 and 4 subunit
• GenBank acession
  • AK222505
• Locus
  21q22.3
• Discovery year
  1986-01-01
• Entrez gene record
  3689
• RefSeq identity
  • NM_000211
• Classification
  • Integrin beta subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000090257
• Locus Specific Databases
  • ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)
  • LRG_76

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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