MKP-2/DUSP4 Antibody, HRP Conjugated
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Catalog numberbs-1852R-HRP
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PricePlease ask
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Size0.1ml
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Long nameMKP-2/DUSP4 Polyclonal Antibody, HRP Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationHRP
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenMKP-2/DUSP4
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SpecificityThis is a highly specific antibody against MKP-2/DUSP4.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic peptide derived from human MKP-2
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Gene ID number1846
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Tested applicationsWB, IHC-P
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundDUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation EmissionN/A
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SynonymsMitogen activated protein kinase phosphatase 2; Dual specicity phosphatase 4; Dual specicity protein phosphatase 4; Dual specicity protein phosphatase hVH2; DUSP 4; HVH 2; HVH2; MAP kinase phosphatase 2; Mitogen activated protein kinase phosphatase 2; MKP 2; MKP2; Serine/threonine specic protein phosphatase; TYP; VH 2; VH1 homologous phosphatase 2; VH2.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
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Additional conjugationHRP Conjugated
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French translationanticorps
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Gene target
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Gene symbolDUSP4, DUSP6, DUSP9, DUSP7, DUSP10, DUSP14, DUSP16, DUSP1, MIR1289-2, MIR521-2
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Short nameAnti-MKP-2/DUSP4
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelHRP
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Alternative nameAnti-MKP-2/DUSP4 PAb HRP
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-03-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 7
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-03-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-11-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 14
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-01-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Atypical dual specificity phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 16
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 1
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-03-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data