MKP-2/DUSP4 Antibody, HRP Conjugated

• Catalog number
  bs-1852R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  MKP-2/DUSP4 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MKP-2/DUSP4
• Specificity
  This is a highly specific antibody against MKP-2/DUSP4.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human MKP-2
• Gene ID number
  1846
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Mitogen activated protein kinase phosphatase 2; Dual specicity phosphatase 4; Dual specicity protein phosphatase 4; Dual specicity protein phosphatase hVH2; DUSP 4; HVH 2; HVH2; MAP kinase phosphatase 2; Mitogen activated protein kinase phosphatase 2; MKP 2; MKP2; Serine/threonine specic protein phosphatase; TYP; VH 2; VH1 homologous phosphatase 2; VH2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  MKP-2/DUSP4   Conjugated  
• Gene symbol
  DUSP4, DUSP6, DUSP9, DUSP7, DUSP10, DUSP14, DUSP16, DUSP1, MIR1289-2, MIR521-2
• Short name
  Anti-MKP-2/DUSP4
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-MKP-2/DUSP4 PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3070
• Gene
  DUSP4
• Long gene name
  dual specificity phosphatase 4
• Synonyms
  • HVH2
  • MKP-2
  • TYP
• Synonyms name
  • VH1 homologous phosphatase 2
  • MAP kinase phosphatase 2
• GenBank acession
  • U21108
• Locus
  8p12
• Discovery year
  1994-12-14
• Entrez gene record
  1846
• Pubmed identfication
  • 7535768
  • 9205128
• RefSeq identity
  • NM_001394
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000133395

Gene info

• Identity
  HGNC:3072
• Gene
  DUSP6
• Long gene name
  dual specificity phosphatase 6
• Synonyms
  • MKP-3
  • PYST1
• GenBank acession
  • BC037236
• Locus
  12q21.33
• Discovery year
  1997-03-19
• Entrez gene record
  1848
• Pubmed identfication
  • 8626780
  • 9205128
• RefSeq identity
  • NM_001946
  • NM_022652
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000169912

Gene info

• Identity
  HGNC:3076
• Gene
  DUSP9
• Long gene name
  dual specificity phosphatase 9
• Synonyms
  • MKP-4
  • MKP4
• Synonyms name
  • map kinase phosphatase 4
• GenBank acession
  • Y08302
• Locus
  Xq28
• Discovery year
  1998-06-25
• Entrez gene record
  1852
• Pubmed identfication
  • 9030581
  • 9286695
• RefSeq identity
  • NM_001395
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000024211

Gene info

• Identity
  HGNC:3073
• Gene
  DUSP7
• Long gene name
  dual specificity phosphatase 7
• Synonyms
  • MKP-X
  • PYST2
• GenBank acession
  • X93921
• Locus
  3p21.2
• Discovery year
  1997-03-19
• Entrez gene record
  1849
• Pubmed identfication
  • 8626780
  • 9205128
• RefSeq identity
  • NM_001947
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000157819

Gene info

• Identity
  HGNC:3065
• Gene
  DUSP10
• Long gene name
  dual specificity phosphatase 10
• Synonyms
  • MKP-5
  • MKP5
• GenBank acession
  • AB026436
• Locus
  1q41
• Discovery year
  1999-11-26
• Entrez gene record
  11221
• Pubmed identfication
  • 10391943
  • 10597297
• RefSeq identity
  • NM_007207
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000037269

Gene info

• Identity
  HGNC:17007
• Gene
  DUSP14
• Long gene name
  dual specificity phosphatase 14
• Synonyms
  • MKP-L
  • MKP6
• Synonyms name
  • MKP-1 like protein tyrosine phosphatase
• GenBank acession
  • AF038844
• Locus
  17q12
• Discovery year
  2002-01-09
• Entrez gene record
  11072
• Pubmed identfication
  • 11123293
• RefSeq identity
  • NM_007026
• Classification
  • Atypical dual specificity phosphatases
• VEGA ID
  OTTHUMG00000188472

Gene info

• Identity
  HGNC:17909
• Gene
  DUSP16
• Long gene name
  dual specificity phosphatase 16
• Synonyms
  • MKP-7
  • KIAA1700
  • MKP7
• Synonyms name
  • MAPK phosphatase-7
• GenBank acession
  • AB052156
• Locus
  12p13.2
• Discovery year
  2002-08-20
• Entrez gene record
  80824
• Pubmed identfication
  • 11359773
  • 11489891
  • 15888437
• RefSeq identity
  • NM_030640
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000168582

Gene info

• Identity
  HGNC:3064
• Gene
  DUSP1
• Long gene name
  dual specificity phosphatase 1
• Synonyms gene
  • PTPN10
• Synonyms
  • HVH1
  • CL100
  • MKP-1
• GenBank acession
  • X68277
• Locus
  5q35.1
• Discovery year
  1993-03-03
• Entrez gene record
  1843
• Pubmed identfication
  • 1406996
  • 7806236
• RefSeq identity
  • NM_004417
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000130523

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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