Ipragliflozin

  • Catalog number
    B1926-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (2S,3R,4R,5S,6R)-2-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
  • Description
    Ipragliflozin is a potent inhibitor of sodium-glucose cotransporter 2 (SGLT2; IC₅₀ = 7.4 nM for human SGLT2 in vitro) that increases excretion of glucose.Iipragliflozin is found to promote preferential loss of fat mass in a rat model of non-obese type 2 diabetes mellitus (T2DM).
  • CAS Number
    761423-87-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₁H₂₁FO₅S
  • Molecular Weight
    404.45
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~30 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent sodium-glucose cotransporter 2 (SGLT2) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    10453870
  • SMILES
    C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)F
  • InChi
    InChI=1S/C21H21FO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1
  • InChi Key
    AHFWIQIYAXSLBA-RQXATKFSSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Ipragliflozin
  • Alternative name
    Ipragliflozin
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