HP1(Tyr43) Antibody, ALEXA FLUOR 350
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Catalog number
bs-0930R-A350
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Price
Please ask
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Size
100ul
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Long name
HP1(Tyr43) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
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Also known as
Anti-HP1 Tyr43 PAb ALEXA FLUOR 350
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 350
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
HP1 Tyr43
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Specificity
This is a highly specific antibody against HP1 Tyr43.
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Modification
Phosphorylation
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Modification Site
Tyr43
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43
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Gene ID Number
34119
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Other Species
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Cross reactive species details
Fruit Fly
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Background of the antigen
HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
343nm/442nm
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Synonyms
Heterochromatin protein 1; HP1; Non-histone chromosomal protein C1A9 antigen; CG8409
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 350
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French translation
anticorps
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Gene target
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Gene symbol
CBX5, HP1BP3, CBX1, TFF1
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Short name
Anti-HP1 Tyr43
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 350
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Alternative name
HP1(Tyr43) Polyclonal Antibody, ALEXA FLUOR 350
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
chromobox 5
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Synonyms gene name
- chromobox homolog 5 (Drosophila HP1 alpha)
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox homolog 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
- MicroRNA protein coding host genes
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
chromobox 1
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Synonyms gene name
- chromobox homolog 1 (Drosophila HP1 beta)
- chromobox homolog 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
trefoil factor 1
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Synonyms gene
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Synonyms gene name
- breast cancer, estrogen-inducible sequence expressed in
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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