anti-SUZ12 Antibody

• Catalog number
  7701
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  The Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation and oncogenesis (1). SUZ12 (suppressor of zeste 12) is a 90 - 95 kDa member of the polycomb group of transcriptional regulators (2). It is part of a transcription repression complex termed PRC2 (Polycomb repressive complex 2) that methylates histones in the nucleus, resulting in homeotic (pattern-inducing) gene silencing. It contains one C2H2-type zinc finger region and a C-terminal VEFS-box (3,4). SUZ12 is overexpressed in breast and colon cancer. SUZ12 may be a cause of endometrial stromal tumors (5).
• Gene names
  SUZ12 Antibody: CHET9, JJAZ1, CHET9, KIAA0160, Polycomb protein SUZ12, Chromatin precipitated E2F target 9 protein, ChET 9 protein
• Antibodie s label
  unlabelled serum
• Purity
  SUZ12 antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  SUZ12 antibody is human specific.
• Antigen
  SUZ12 antibody was made against a 19 amino acid peptide near the center of human SUZ12.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  SUZ12 antibody can be used for detection of SUZ12 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  SUZ12 antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  SUZ12 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human
• Omim nr
  197333809
• Ncbi nr
  NP_056170
• KDa
  Predicted: 81 kDa Observed: 96 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  23512
• GENE symbol
  SUZ12
• Antigene name
  SUZ12 polycomb repressive complex 2 subunit
• Source
  homo sapiens
• Protein nr
  Q15022
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SUZ12  
• Gene symbol
  SUZ12
• Short name
  anti-SUZ12 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSUZ12 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17101
• Gene
  SUZ12
• Long gene name
  SUZ12 polycomb repressive complex 2 subunit
• Synonyms gene name
  • suppressor of zeste 12 homolog (Drosophila)
• Synonyms
  • JJAZ1
  • KIAA0160
  • CHET9
• GenBank acession
  • D63881
• Locus
  17q11.2
• Discovery year
  2004-12-14
• Entrez gene record
  23512
• Pubmed identfication
  • 8590280
  • 11371647
  • 18784248
• RefSeq identity
  • NM_015355
• Classification
  • Polycomb repressive complex 2
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000132813

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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