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Varlitinib for cell activation

Varlitinib for cell activation is available 2 times from Biovision labs

2656-5 | Varlitinib for cell activation size: 5 mg | 242.56 USD

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2656-25 | Varlitinib for cell activation size: 25 mg | 801.90 USD

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Description Varlitinib is a potent inhibitor of the epidermal growth factor receptor (EGFR) family with potential antineoplastic activity. Varlitinib selectively and reversibly binds to both EGFR (ErbB-1) and Her-2/neu (ErbB-2) and prevents their phosphorylation and activation, which may result in inhibition of the associated signal transduction pathways, inhibition of cellular proliferation and cell death. EGFR and Her-2 play important roles in cell proliferation and differentiation and are upregulated in various human tumor cell types. Due to the dual inhibition of both EGFR and Her-2, this agent may be therapeutically more effective than agents that inhibit EGFR or Her-2 alone. 
Peptide sequence N/A
CAS number 845272-21-1
Molecular weight 466.94
Category Biochemicals
Other name (R)-N4-(3-chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine
Molecular formula C₂₂H₁₉ClN₆O₂S
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetVarlitinib for activation
Short name Varlitinib for activation
Technique activation
Alternative name Varlitinib to measure cellular activation
Tissue cell
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