ABT-263

• Catalog number
  2467-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (R)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide; Navitoclax
• Description
  A potent, small molecule Bcl-2 family protein inhibitor (Ki’s of
• CAS Number
  923564-51-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₄₅H₅₅ClF₃N₅O₆S₃
• Molecular Weight
  974.61
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (> 50 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An inhibitor of antiapoptotic Bcl-2 proteins
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• PubChem CID
  24978538
• PubChem CID Link
• SMILES
  CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
• InChi
  InChI=1S/C47H55ClF3N5O6S3/c1-46(2)20-18-42(34-8-12-37(48)13-9-34)36(31-46)32-55-22-24-56(25-23-55)39-14-10-35(11-15-39)45(57)53-65(60,61)41-16-17-43(44(30-41)64(58,59)47(49,50)51)52-38(19-21-54-26-28-62-29-27-54)33-63-40-6-4-3-5-7-40/h3-17,30,38,52H,18-29,31-33H2,1-2H3,(H,53,57)/t38-/m1/s1
• InChi Key
  JLYAXFNOILIKPP-KXQOOQHDSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  ABT-263  
• Short name
  ABT-263
• Alternative name
  ABT-263

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