Anti-IDH1 Antibody
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Catalog numberA1383-100
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PricePlease ask
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Size100 µg
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Antibody TargetIDH1
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Target Alternative NameIsocitrate dehydrogenase [NADP] cytoplasmic, R132H, IDH 1 R132H
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Antibody TypePolyclonal
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Species ReactivitiesHuman
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Immunogen SequenceHuman recombinant IDH1
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AccessionO75874
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Gene Id3417
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AppearanceColorless liquid
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FormLiquid
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FormulationIn PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
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PurificationAffinity purified
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ApplicationWestern blot
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Positive ControlWestern blot
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Application And UsagesWestern blot: 1-4 µg/ml
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DescriptionMutations of the cytosolic IDH 1 are a common feature in primary human brain cancers. Arginine 132 (R132) of IDH is highly conserved among different isoforms of IDH and is most commonly mutated to Histidine. Mutation of IDH1 R132H leads to accumulation of R(-)-2-hydroxyglutarate (2HG), which correlates with an increased risk for malignant brain tumors.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIDH1, IDH1-AS1
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Short nameAnti-IDH1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibody toIDH1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameisocitrate dehydrogenase (NADP(+)) 1
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Synonyms gene name
- isocitrate dehydrogenase 1 (NADP+), soluble
- isocitrate dehydrogenase 1 (NADP+)
- isocitrate dehydrogenase (NADP(+)) 1, cytosolic
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Isocitrate dehydrogenases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameIDH1 antisense RNA 1
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Synonyms gene name
- IDH1 antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2012-02-24
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Entrez gene record
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Classification
- Antisense RNAs
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data