Anti-IDH1 Antibody

• Catalog number
  A1383-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  IDH1
• Target Alternative Name
  Isocitrate dehydrogenase [NADP] cytoplasmic, R132H, IDH 1 R132H
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Human recombinant IDH1
• Accession
  O75874
• Gene Id
  3417
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Western blot
• Application And Usages
  Western blot: 1-4 µg/ml
• Description
  Mutations of the cytosolic IDH 1 are a common feature in primary human brain cancers. Arginine 132 (R132) of IDH is highly conserved among different isoforms of IDH and is most commonly mutated to Histidine. Mutation of IDH1 R132H leads to accumulation of R(-)-2-hydroxyglutarate (2HG), which correlates with an increased risk for malignant brain tumors.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IDH1  
• Gene symbol
  IDH1, IDH1-AS1
• Short name
  Anti-IDH1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toIDH1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5382
• Gene
  IDH1
• Long gene name
  isocitrate dehydrogenase (NADP(+)) 1
• Synonyms gene name
  • isocitrate dehydrogenase 1 (NADP+), soluble
  • isocitrate dehydrogenase 1 (NADP+)
  • isocitrate dehydrogenase (NADP(+)) 1, cytosolic
• Locus
  2q34
• Discovery year
  2001-06-22
• Entrez gene record
  3417
• RefSeq identity
  • NM_005896
• Classification
  • Isocitrate dehydrogenases
• VEGA ID
  OTTHUMG00000132943
• Locus Specific Databases
  • LRG_610

Gene info

• Identity
  HGNC:40292
• Gene
  IDH1-AS1
• Long gene name
  IDH1 antisense RNA 1
• Synonyms gene name
  • IDH1 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AI492612
  • BE465811
• Locus
  2q34
• Discovery year
  2012-02-24
• Entrez gene record
  100507475
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000154707

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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