Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

Amifostine HIF 1α activator

Amifostine HIF 1α activator is available 2 times from Stressma labs

SIH-210-50MG | Amifostine, HIF-1α activator size: 50 mg | 375.43 USD

Loading

SIH-210-10MG | Amifostine, HIF-1α activator size: 10 mg | 135.60 USD

Catalog number SIH-210-10MG
Supplier stressma
Price 135.60 USD
Size 10 mg
Net weight (g) 0.01
1. Gene info
Identity 700
Gene ARNT
Long gene name aryl hydrocarbon receptor nuclear translocator
Synonyms
  • HIF-1beta
  • bHLHe2
GenBank acession
  • AF001307
Locus 1q21.3
Discovery year 1990-01-22
Entrez gene record 405
Classification
  • Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000035011
2. Gene info
Identity 4910
Gene HIF1A
Long gene name hypoxia inducible factor 1 alpha subunit
Synonyms gene name
  • hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Synonyms
  • MOP1
  • HIF-1alpha
  • PASD8
  • HIF1
  • bHLHe78
GenBank acession
  • U22431
Locus 14q23.2
Discovery year 1995-03-27
Entrez gene record 3091
Pubmed identfication
  • 8786149
  • 9079689
RefSeq identity
  • NM_001530
Classification
  • Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000140344
MeSH Data
Name Amifostine
Tree numbers
  • D02.705.400.625.050
  • D02.705.539.345.050
  • D02.886.300.692.050
Origin Synthetic
Soluble in Soluble in water
Other name S-{2-[(3-Aminopropyl)amino]ethyl} dihydrogen phosphorothioate
PubMed number Refer to PubMed
Description HIF-1α activator
Warning information Non-hazardous
Representative figure legend Chemical structure of Amifostine (SIH-210), a Cellular protectant. CAS #: 20537-88-6. Molecular Formula: C5H15N2O3PS. Molecular Weight: 214.22 g/mol. Chemical structure of Amifostine, a Cellular protectant (SIH-210). CAS # 20537-88-6. Molecular Formula: C5H15N2O3PS.
Stock availabilitIn Stock In Stock
Molecular weight 214,22 g/mol
Purity pourcentage >98%
Chemical formula C5H15N2O3PS
Tested applications To be tested
Primary research fields Cancer, Apoptosis
Total weight (kg) 0.25
Release date 16-May-2011
Scientific context Amifostine is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy. Inside cells it detoxifies reactive metabolites of platinum and alkylating agents (1, 2). Other effects include accelerated DNA repair (1), induction of cellular hypoxia (1), inhibition of apoptosis (2), alteration of gene expression (2) and modification of enzyme activity (2).
Product type Activator
CAS number 20537-88-6
Safety information Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
Country of production Canada
Product category Small Molecules
Physical appearance White Solid
Tested reactivity To be tested
PubChem number 2141
Bibliography 1. Kouvaris J.R., Kouloulias V.E., Blahos L.J. (2007) Oncologist. 12(6): 738-747. 2. Amifostine: BC Cancer Agency. 2006-03-01.
Storage recommendations -20ºC
Shipping recommendations Shipped Ambient
Gene targetAmifostine HIF-1α activator
Short name Amifostine, HIF-1α activator
Alternative name Amifostine, HIF-1α activator
Similar products
Amifostine HIF 1α activator Suppplier: StressMarq
Price: 304.83 USD
Ask
Ajax processing
Close
Amifostine, HIF-1α activator size: 10 mg - Gentaur.com
Filters
+32-(0)1-658-90-45 [email protected]
  • Amifostine
  • HIF-1α
  • activator
Back
Contact us
Ajax processing
Close
Chat with gentaur.com employee