Carbamazepine

  • Catalog number
    B2401-250
  • Price
    Please ask
  • Size
    250 mg
  • Alternative_name
    5H-Dibenz[b,f]azepine-5-carboxamide, CBZ
  • Description
    Carbamazepine is an inhibitor of neuronal voltage-gated Na+ channels. It displays anticonvulsant activity and potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also acts as an in vitro inducer of CYP3A4, the main human metabolizing enzyme present in the liver and intestine.
  • CAS Number
    298-46-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₅H₁₂N₂O
  • Molecular Weight
    236.27
  • Cell Permeable
    False
  • Purity
    ≥98% by HPLC
  • Solubilities
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    Inhibitor of neuronal NaV channels
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00005073
  • PubChem CID
    2554
  • SMILES
    C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N
  • InChi
    InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
  • InChi Key
    FFGPTBGBLSHEPO-UHFFFAOYSA-N
  • MSDS Available
    True
  • Gene target
  • Short name
    Carbamazepine
  • Alternative name
    Carbamazepine
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