Anti-MRP8+MRP14 (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-7870R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  MRP8+MRP14
• Specificity
  This antibody reacts specifically with MRP8+MRP14
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human MRP8+MRP14
• Gene ID
  85320
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq].
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  MRP 14; MRP-14; MRP 8; MRP8; MRP-8; N; P14; P8; Protein S100 A8; Protein S100 A9; S100 A8; S100 A9; S100 calcium binding protein A8; S100 calcium binding protein A9; S100A8; S100A9; Urinary stone protein band A; 60B8AG; CAGA; CAGB; Calgranulin A; Calgranulin B; Calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; CP 10; CP10; Cystic fibrosis antigen; L1AG; Leukocyte L1 complex heavy chain; Leukocyte L1 complex light chain; LIAG; MA387; MAC387; M; MRP8 + MRP14; Migration inhibitory factor related protein 14; Migration inhibitory factor related protein 8.
• Also known as
  MRP8+MRP14 Polyclonal Antibody
• Other name
  Anti-MRP8+MRP14 Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  MRP8+MRP14  
• Gene symbol
  ABCC11, ABCC8, S100A8, S100A9
• Short name
  Anti-MRP8+MRP14
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  MRP8+MRP14 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:14639
• Gene
  ABCC11
• Long gene name
  ATP binding cassette subfamily C member 11
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11
• Synonyms
  • MRP8
• GenBank acession
  • AF367202
• Locus
  16q12.1
• Discovery year
  2001-06-01
• Entrez gene record
  85320
• Pubmed identfication
  • 11483364
  • 11435397
• RefSeq identity
  • NM_032583
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000133146

Gene info

• Identity
  HGNC:59
• Gene
  ABCC8
• Long gene name
  ATP binding cassette subfamily C member 8
• Synonyms gene
  • SUR
  • HRINS
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
• Synonyms
  • HI
  • PHHI
  • SUR1
  • MRP8
  • ABC36
  • HHF1
  • TNDM2
• Synonyms name
  • sulfonylurea receptor (hyperinsulinemia)
• GenBank acession
  • L78207
• Locus
  11p15.1
• Discovery year
  1995-01-10
• Entrez gene record
  6833
• Pubmed identfication
  • 7920639
  • 7716548
• RefSeq identity
  • NM_000352
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000166316
• Locus Specific Databases
  • LRG_790

Gene info

• Identity
  HGNC:10498
• Gene
  S100A8
• Long gene name
  S100 calcium binding protein A8
• Synonyms gene
  • CAGA
  • CFAG
• Synonyms gene name
  • calgranulin A
  • cystic fibrosis antigen
• Synonyms
  • P8
  • MRP8
  • MRP-8
  • 60B8AG
  • CGLA
  • S100-A8
• Synonyms name
  • Migration inhibitory factor-related protein 8
  • Calprotectin L1L subunit
  • Leukocyte L1 complex light chain
• GenBank acession
  • BC005928
• Locus
  1q21.3
• Discovery year
  1989-05-19
• Entrez gene record
  6279
• RefSeq identity
  • NM_002964
• Classification
  • S100 calcium binding proteins
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000013124

Gene info

• Identity
  HGNC:10499
• Gene
  S100A9
• Long gene name
  S100 calcium binding protein A9
• Synonyms gene
  • CAGB
  • CFAG
• Synonyms gene name
  • calgranulin B
  • S100 calcium-binding protein A9 (calgranulin B)
• Synonyms
  • P14
  • MIF
  • NIF
  • LIAG
  • MRP14
  • MAC387
  • 60B8AG
  • CGLB
  • MRP-14
  • S100-A9
• Synonyms name
  • Calprotectin L1H subunit
  • Leukocyte L1 complex heavy chain
  • Migration inhibitory factor-related protein 14
• GenBank acession
  • BC047681
• Locus
  1q21.3
• Discovery year
  1989-05-19
• Entrez gene record
  6280
• RefSeq identity
  • NM_002965
• Classification
  • S100 calcium binding proteins
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000013125

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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