NGB/neuroglobin Antibody, ALEXA FLUOR 488

• Catalog number
  bs-1859R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  NGB/neuroglobin Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-NGB/neuroglobin PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  NGB/neuroglobin
• Specificity
  This is a highly specific antibody against NGB/neuroglobin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  100-150/150
• Subcellular location
  Cytoplasm, Mitochondrion
• Source
  KLH conjugated synthetic peptide derived from mouse NGB
• Gene ID Number
  64242
• Swiss Prot
  Q9ER97
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Neuroglobin; Ngb
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-NGB/neuroglobin has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  NGB/neuroglobin  
• Gene symbol
  NGB, GTPBP4
• Short name
  Anti-NGB/neuroglobin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  NGB/neuroglobin Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14077
• Gene
  NGB
• Long gene name
  neuroglobin
• GenBank acession
  • AJ245946
• Locus
  14q24.3
• Discovery year
  2000-11-28
• Entrez gene record
  58157
• Pubmed identfication
  • 11029004
  • 17210637
• RefSeq identity
  • NM_021257
• VEGA ID
  OTTHUMG00000171558

Gene info

• Identity
  HGNC:21535
• Gene
  GTPBP4
• Long gene name
  GTP binding protein 4
• Synonyms
  • CRFG
  • NGB
  • FLJ10690
  • FLJ10686
  • NOG1
• Synonyms name
  • G protein-binding protein CRFG
  • GTP-binding protein
• GenBank acession
  • AK001548
• Locus
  10p15.3
• Discovery year
  2003-08-11
• Entrez gene record
  23560
• Pubmed identfication
  • 11316846
• RefSeq identity
  • NM_012341
• VEGA ID
  OTTHUMG00000017538

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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