VE-821

• Catalog number
  B1723-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  VE-821; VE821; VE 821; 3-amino-6-(4-methylsulfonylphenyl)-N-phenylpyrazine-2-carboxamide
• Description
  VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM.
• CAS Number
  1232410-49-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₆N₄O₃S
• Molecular Weight
  368.41
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent and selective ATR inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD19443686
• PubChem CID
  51000408
• PubChem CID Link
• SMILES
  CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N
• InChi
  InChI=1S/C18H16N4O3S/c1-26(24,25)14-9-7-12(8-10-14)15-11-20-17(19)16(22-15)18(23)21-13-5-3-2-4-6-13/h2-11H,1H3,(H2,19,20)(H,21,23)
• InChi Key
  DUIHHZKTCSNTGM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  VE-821  
• Gene symbol
  JAM2
• Short name
  VE-821
• Alternative name
  VE-821

Gene info

• Identity
  HGNC:14686
• Gene
  JAM2
• Long gene name
  junctional adhesion molecule 2
• Synonyms gene
  • C21orf43
• Synonyms
  • VE-JAM
  • JAM-B
  • JAMB
  • CD322
• GenBank acession
  • AF255910
• Locus
  21q21.3
• Discovery year
  2001-04-25
• Entrez gene record
  58494
• Pubmed identfication
  • 10779521
  • 10945976
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000078441

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