FX1
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Catalog numberB2010-25
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PricePlease ask
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Size25 mg
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Alternative_name(5Z)-5-(5-Chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinepropanoic acid
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DescriptionFX1 is a potent B cell lymphoma 6 (BCL6) inhibitor. FX1 displays 10-fold greater potency than endogenous corepressors and binds an essential region of the BCL6 lateral groove. FX1 disrupts formation of the BCL6 repression complex, reactivated BCL6 target genes, and mimics the phenotype of mice engineered to express BCL6 with corepressor binding site mutations.
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CAS Number1426138-42-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₄H₉ClN₂O₄S₂
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Molecular Weight368.81
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent B cell lymphoma 6 (BCL6) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID66488970
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SMILESC1=CC2=C(C=C1Cl)C(=C3C(=O)N(C(=S)S3)CCC(=O)O)C(=O)N2
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InChiInChI=1S/C14H9ClN2O4S2/c15-6-1-2-8-7(5-6)10(12(20)16-8)11-13(21)17(14(22)23-11)4-3-9(18)19/h1-2,5H,3-4H2,(H,16,20)(H,18,19)/b11-10-
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InChi KeyVISHSGZPGQKEFX-KHPPLWFESA-N
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MSDS AvailableYes
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Gene target
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Short nameFX1
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Alternative nameFX1
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