FX1

  • Catalog number
    B2010-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    (5Z)-5-(5-Chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinepropanoic acid
  • Description
    FX1 is a potent B cell lymphoma 6 (BCL6) inhibitor. FX1 displays 10-fold greater potency than endogenous corepressors and binds an essential region of the BCL6 lateral groove. FX1 disrupts formation of the BCL6 repression complex, reactivated BCL6 target genes, and mimics the phenotype of mice engineered to express BCL6 with corepressor binding site mutations. 
  • CAS Number
    1426138-42-2 
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₄H₉ClN₂O₄S₂
  • Molecular Weight
    368.81
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent B cell lymphoma 6 (BCL6) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    66488970
  • SMILES
    C1=CC2=C(C=C1Cl)C(=C3C(=O)N(C(=S)S3)CCC(=O)O)C(=O)N2
  • InChi
    InChI=1S/C14H9ClN2O4S2/c15-6-1-2-8-7(5-6)10(12(20)16-8)11-13(21)17(14(22)23-11)4-3-9(18)19/h1-2,5H,3-4H2,(H,16,20)(H,18,19)/b11-10-
  • InChi Key
    VISHSGZPGQKEFX-KHPPLWFESA-N
  • MSDS Available
    Yes
  • Gene target
    FX1  
  • Short name
    FX1
  • Alternative name
    FX1
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