Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 12 (TNFSF12)

• Catalog number
  RPU44234-100ug
• Price
  Please ask
• Size
  100ug

• Estimated Turnaround Time
  6-11 business days
• Gene Name
  NA
• Alternative Names
  APO3L; DR3LG; TWEAK; APO3 ligand; TNF-related weak inducer of apoptosis
• Source
  E.coli
• Purity
  ≥ 98%
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  1 year
• Restriction
  For research use only. Not for diagnostic procedures.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tumor   Necrosis   Factor   Ligand   Superfamily   Member   TNFSF12  
• Gene symbol
  TNFSF12, TNFSF12-TNFSF13
• Short name
  Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 12 (TNFSF12)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Homo sapiens (Human)
• Alternative name
  Rec. Tumor Necrosis Factor Ligand supergroup, Member 12 (tumor necrosis factor (ligand) superfamily, member 12)
• Alternative technique
  rec
• Alternative to gene target
  tumor necrosis factor (ligand) superfamily, member 12, APO3L and DR3LG and TWEAK, TNFSF12 and IDBG-408330 and ENSG00000239697 and 8742, protein binding, Extracellular, Tnfsf12 and IDBG-708803 and ENSMUSG00000097328 and 21944, TNFSF12 and IDBG-634998 and ENSBTAG00000031725 and 100551513,517833,788103
• Tissue
  tumor

Gene info

• Identity
  HGNC:11927
• Gene
  TNFSF12
• Long gene name
  TNF superfamily member 12
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 12
• Synonyms
  • TWEAK
  • DR3LG
  • APO3L
• GenBank acession
  • AF030099
• Locus
  17p13.1
• Discovery year
  1998-12-04
• Entrez gene record
  8742
• Pubmed identfication
  • 9405449
  • 9560343
• RefSeq identity
  • NM_003809
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000108148
• Locus Specific Databases
  • LRG_1320

Gene info

• Identity
  HGNC:33537
• Gene
  TNFSF12-TNFSF13
• Long gene name
  TNFSF12-TNFSF13 readthrough
• Synonyms
  • TWE-PRIL
• GenBank acession
  • AY081051
• Locus
  17p13.1
• Discovery year
  2007-07-31
• Entrez gene record
  407977
• Pubmed identfication
  • 12411489
• VEGA ID
  OTTHUMG00000161573

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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