Fibronectin Antibody, ALEXA FLUOR 488

  • Catalog number
    bs-4859R-A488
  • Price
    Please ask
  • Size
    100ul
  • Long name
    Fibronectin Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
  • Also known as
    Anti-Fibronectin PAb ALEXA FLUOR 488
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 488
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Fibronectin
  • Specificity
    This is a highly specific antibody against Fibronectin.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    1500-1550/2386
  • Subcellular location
    Secreted
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibronectin Ugl-Y3
  • Gene ID Number
    2335
  • Swiss Prot
    P02751
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    499nm/519nm
  • Synonyms
    FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; Fibronectin; Cold-insoluble globulin; FN1
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Fibronectin has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    FANK1, FNDC3A, FLRT3
  • Short name
    Anti-Fibronectin
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 488
  • Alternative name
    Fibronectin Polyclonal Antibody, ALEXA FLUOR 488
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    fibronectin type III and ankyrin repeat domains 1
  • Synonyms gene name
    • fibronectin type 3 and ankyrin repeat domains 1
  • GenBank acession
  • Locus
  • Discovery year
    2003-11-21
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Ankyrin repeat domain containing
    • Fibronectin type III domain containing
  • VEGA ID
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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