PTF1A Polyclonal Antibody

• Catalog number
  CAC08024
• Price
  Please ask
• Size
  100 μg

• Other name
  Pancreas transcription factor 1 subunit alpha,Class A basic helix-loop-helix protein 29,bHLHa29,Pancreas-specific transcription factor 1a,bHLH transcription factor p48,p48 DNA-binding subunit of transcription factor PTF1,PTF1-p48,PTF1A,BHLHA29,PTF1P48
• Immunogen
  Recombinant Human Pancreas transcription factor 1 subunit alpha protein (224-325AA)
• Verified reactivity
  Human, Mouse, Rat
• Verified applications
  ELISA,WB,IHC,IF. Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200,IF:1:50-1:200
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  Q7RTS3
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  PTF1A  
• Gene symbol
  PTF1A
• Short name
  PTF1A Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  PTF1A polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:23734
• Gene
  PTF1A
• Long gene name
  pancreas associated transcription factor 1a
• Synonyms gene name
  • pancreas specific transcription factor, 1a
• Synonyms
  • PTF1-p48
  • bHLHa29
  • p48
• GenBank acession
  • BK000272
• Locus
  10p12.2
• Discovery year
  2003-12-04
• Entrez gene record
  256297
• Pubmed identfication
  • 8703005
• RefSeq identity
  • NM_178161
• Classification
  • PTF1 complex
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000017815

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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