SB-715992

• Catalog number
  2468-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide; Ispinesib; CK0238273
• Description
  A potent, reversible, small molecule inhibitor of kinesin spindle protein (KSP), a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis. Displays anticancer properties.
• CAS Number
  336113-53-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₀H₃₃ClN₄O₂
• Molecular Weight
  517.06
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (> 50 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, reversible, kinesin spindle protein (KSP) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• PubChem CID
  6851740
• PubChem CID Link
• SMILES
  CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
• InChi
  InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
• InChi Key
  QJZRFPJCWMNVAV-HHHXNRCGSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  SB-715992  
• Short name
  SB-715992
• Alternative name
  SB-715992

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