LGI1 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-6719R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  LGI1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-LGI1 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LGI1
• Specificity
  This is a highly specific antibody against LGI1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  480-530/557
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LGI1
• Gene ID Number
  9211
• Swiss Prot
  O95970
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN; Leucine-rich glioma-inactivated protein 1; Epitempin-1; LGI1; UNQ775/PRO1569
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-LGI1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  LGI1  
• Gene symbol
  LGI1
• Short name
  Anti-LGI1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  LGI1 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6572
• Gene
  LGI1
• Long gene name
  leucine rich glioma inactivated 1
• Synonyms gene
  • EPT
• Synonyms gene name
  • epilepsy, partial
• Synonyms
  • IB1099
  • ETL1
  • EPITEMPIN
• GenBank acession
  • AF055636
• Locus
  10q23.33
• Discovery year
  1998-09-25
• Entrez gene record
  9211
• Pubmed identfication
  • 9879993
  • 11978770
  • 15079011
• RefSeq identity
  • NM_005097
• Classification
  • LGI family
• VEGA ID
  OTTHUMG00000018777

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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