BQ-123 Sodium Salt

• Catalog number
  B1552-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  Cyclo (D-Trp-D-Asp-Pro-D-Val-Leu) ; Endothelin Receptor A Antagonist BQ-123
• Description
  BQ-123 sodium is a potent and selective ETA endothelin receptor antagonist (Ki values are 1.4 and 1500 nM at ETA and ETB receptors respectively). It also inhibits ET-1 receptor binding and blocks Ca²⁺ mobilization, cellular contraction and MAP kinase activation.
• CAS Number
  136553-81-6 (Free acid)
• Structure Available
  Yes
• Peptide sequence
  Cyclo (D-Trp-D-Asp-Pro-D-Val-Leu)
• Molecular Formula
  C₃₁H₄₂N₆O₇•Na
• Molecular Weight
  633.69
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  H₂O
• Handling
  Protect from air and moisture
• Tag Line
  A potent and selective ETA endothelin receptor antagonist
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00133204
• PubChem CID
  443289
• PubChem CID Link
• SMILES
  CC(C)CC1C(=O)NC(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)N1)C(C)C)CC(=O)O)CC3=CNC4=CC=CC=C43
• InChi
  InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23+,24-,26+/m0/s1
• InChi Key
  VYCMAAOURFJIHD-PJNXIOHISA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BQ-123   Sodium   Salt  
• Gene symbol
  RNF11, SNHG12, OR5B1P
• Short name
  BQ-123 Sodium Salt
• Alternative name
  BQ-123 Sodium Salt

Gene info

• Identity
  HGNC:10056
• Gene
  RNF11
• Long gene name
  ring finger protein 11
• Synonyms
  • CGI-123
  • Sid1669p
  • MGC51169
• GenBank acession
  • AB024703
• Locus
  1p32.3
• Discovery year
  2000-01-07
• Entrez gene record
  26994
• Pubmed identfication
  • 10673045
  • 10810093
• RefSeq identity
  • NM_014372
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000008190

Gene info

• Identity
  HGNC:30062
• Gene
  SNHG12
• Long gene name
  small nucleolar RNA host gene 12
• Synonyms gene
  • C1orf79
• Synonyms gene name
  • chromosome 1 open reading frame 79
  • small nucleolar RNA host gene 12 (non-protein coding)
• Synonyms
  • PNAS-123
  • LINC00100
  • ASLNC04080
• Synonyms name
  • long intergenic non-protein coding RNA 100
• GenBank acession
  • AF277181
  • KJ782215
• Locus
  1p35.3
• Discovery year
  2005-05-24
• Entrez gene record
  85028
• Pubmed identfication
  • 25695231
  • 27980086
• RefSeq identity
  • NR_024127
• Classification
  • Small nucleolar RNA non-coding host genes
• VEGA ID
  OTTHUMG00000003654

Gene info

• Identity
  HGNC:8322
• Gene
  OR5B1P
• Long gene name
  olfactory receptor family 5 subfamily B member 1 pseudogene
• Synonyms gene
  • OR5B9P
  • OR5B9
  • OR5B5P
  • OR5B14P
  • OR5B7P
  • OR5B7
  • OR5B8
  • OR5B8P
  • OR5B5
  • OR5B6
  • OR5B6P
• Synonyms gene name
  • olfactory receptor, family 5, subfamily B, member 1 pseudogene
• Synonyms
  • OR8-122
  • OR8-123
  • OR6-57
  • OR6-55
  • OR3-144
  • OR912-92
• GenBank acession
  • U86283
• Locus
  11q12.1
• Discovery year
  1999-11-25
• Entrez gene record
  401692
• Pubmed identfication
  • 9500546
• Classification
  • Olfactory receptors, family 5
• VEGA ID
  OTTHUMG00000154286

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