GSK1325756
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Catalog numberB1103-1
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PricePlease ask
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Size1 mg
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Alternative_name1-[4-chloro-2-hydroxy-3-[(3S)-piperidin-3-yl]sulfonylphenyl]-3-(3-fluoro-2-methylphenyl)urea; Danirixin
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DescriptionGSK1325756 is a selective and reversible CXCR2 antagonist with IC₅₀ value of 12.5 nM. GSK1325756 displays anti-inflammatory effects in various preclinical and clinical models.
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CAS Number954126-98-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₉H₂₁ClFN₃O₄S
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Molecular Weight441.9
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (> 8 mg/ml)
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HandlingProtect from air and light
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Tag LineGSK1325756 is selective and reversible CXCR2 antogonist
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID24780598
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SMILESCC1=C(C=CC=C1F)NC(=O)NC2=C(C(=C(C=C2)Cl)S(=O)(=O)C3CCCNC3)O
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InChiInChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1
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InChi KeyNGYNBSHYFOFVLS-LBPRGKRZSA-N
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MSDS AvailableYes
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Gene target
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Short nameGSK1325756
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Alternative nameGSK1325756
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