GSK1325756

  • Catalog number
    B1103-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    1-[4-chloro-2-hydroxy-3-[(3S)-piperidin-3-yl]sulfonylphenyl]-3-(3-fluoro-2-methylphenyl)urea; Danirixin
  • Description
    GSK1325756 is a selective and reversible CXCR2 antagonist with IC₅₀ value of 12.5 nM. GSK1325756 displays anti-inflammatory effects in various preclinical and clinical models.
  • CAS Number
    954126-98-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₉H₂₁ClFN₃O₄S
  • Molecular Weight
    441.9
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (> 8 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    GSK1325756 is selective and reversible CXCR2 antogonist
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    24780598
  • SMILES
    CC1=C(C=CC=C1F)NC(=O)NC2=C(C(=C(C=C2)Cl)S(=O)(=O)C3CCCNC3)O
  • InChi
    InChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1
  • InChi Key
    NGYNBSHYFOFVLS-LBPRGKRZSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    GSK1325756
  • Alternative name
    GSK1325756
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