CITED2 Antibody (NT)

• Catalog number
  5286-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  CITED2
• Target Alternative Name
  Cbp/p300-interacting transactivator 2, melanocyte-specific gene 1-related gene 1, MSG-related protein 1, MRG1, melanocyte specific gene 2, MSG2, ER154-like, ASD8, VSD2
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  CITED2 antibody was raised against an 18 amino acid peptide near the amino terminus of human CITED2.
• Accession
  Q99967
• Gene Id
  10370
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  100 µg (1 mg/ml) in 1X PBS containing 0.02 % sodium azide.
• Purification
  Affinity chromatography purified via peptide column
• Application
  Western blot, ELISA
• Positive Control
  Western Blot: Jurkat cell lysate
• Application And Usages
  Western Blot: 1 - 2 μg/ml, ELISA. However, the optimal conditions should be determined individually.
• Description
  CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CITED2  
• Gene symbol
  CITED2
• Short name
  CITED2 Antibody (NT)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG1
• Alternative name
  Cbp/p300-interacting transactivator, including L-gutamic acid/L-aspartic acid-rich carboxy-terminal domain, 2 (antibody to-) (NT)
• Alternative technique
  antibodies
• Alternative to gene target
  Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, ASD8 and MRG-1 and MRG1 and P35SRJ and VSD2, CITED2 and IDBG-97161 and ENSG00000164442 and 10370, LBD domain binding, nuclei, Cited2 and IDBG-134872 and ENSMUSG00000039910 and 17684, CITED2 and IDBG-633814 and ENSBTAG00000011224 and 521378

Gene info

• Identity
  HGNC:1987
• Gene
  CITED2
• Long gene name
  Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
• Synonyms gene name
  • Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2
• Synonyms
  • MRG1
• GenBank acession
  • U65093
• Locus
  6q24.1
• Discovery year
  1999-06-11
• Entrez gene record
  10370
• Pubmed identfication
  • 8901575
  • 10552932
• VEGA ID
  OTTHUMG00000015691

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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