VX-222

• Catalog number
  B2207-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid; Lomibuvir; VCH-222
• Description
  VX-222 is a potent, non-nucleoside inhibitor of HCV polymerase (IC₅₀ = 0.94-1.2 μM). It is 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.
• CAS Number
  1026785-59-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₃₅NO₄S
• Molecular Weight
  445.6
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, non-nucleoside inhibitor of HCV polymerase
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  24798764
• PubChem CID Link
• SMILES
  CC1CCC(CC1)C(=O)N(C2CCC(CC2)O)C3=C(SC(=C3)C#CC(C)(C)C)C(=O)O
• InChi
  InChI=1S/C25H35NO4S/c1-16-5-7-17(8-6-16)23(28)26(18-9-11-19(27)12-10-18)21-15-20(13-14-25(2,3)4)31-22(21)24(29)30/h15-19,27H,5-12H2,1-4H3,(H,29,30)
• InChi Key
  WPMJNLCLKAKMLA-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  VX-222  
• Gene symbol
  MIR222
• Short name
  VX-222
• Alternative name
  VX-222

Gene info

• Identity
  HGNC:31602
• Gene
  MIR222
• Long gene name
  microRNA 222
• Synonyms gene
  • MIRN222
• Synonyms
  • hsa-mir-222
• Locus
  Xp11.3
• Discovery year
  2004-04-23
• Entrez gene record
  407007
• RefSeq identity
  • NR_029636
• Classification
  • MicroRNAs

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