Bioymifi

  • Catalog number
    9424-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    (Z)-5-(5-[(3-[4-Bromophenyl]-2-imino-4-oxothiazolidin-5-ylidene)methyl]furan-2-yl)isoindoline-1,3-dione
  • Description
    Bioymifi is a potent and selective death receptor 5 (DR5) activator. Bioymifi works by mimicking the ability of TRAIL, the natural DR5 ligand, to stimulate clustering of DR5, triggering apoptosis. Bioymifi caused apoptosis and cell death in a variety of human cancer cell lines including T98G human glioblastoma cells, lung cancer cell lines H460 and H1155, the cervical cancer cell line HeLa, the osteosarcoma cell line U2OS, the pancreatic carcinoma cell line Miapaca and the colon cancer cell line HT29.
  • CAS Number
    1420071-30-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₂H₁₂BrN₃O₄S
  • Molecular Weight
    494.32
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~ 2 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective death receptor 5 (DR5) activator
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    70678419
  • SMILES
    C1=CC(=CC=C1N2C(=O)C(=CC3=CC=C(O3)C4=CC5=C(C=C4)C(=O)NC5=O)SC2=N)Br
  • InChi
    InChI=1S/C22H12BrN3O4S/c23-12-2-4-13(5-3-12)26-21(29)18(31-22(26)24)10-14-6-8-17(30-14)11-1-7-15-16(9-11)20(28)25-19(15)27/h1-10,24H,(H,25,27,28)/b18-10-,24-22?
  • InChi Key
    ULBOWKXOFOTCMU-NLDKGBHCSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Bioymifi
  • Alternative name
    Bioymifi
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