NS-3763
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Catalog numberB1814-25
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PricePlease ask
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Size25 mg
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Alternative_name4,6-Bis(benzoylamino)-1,3-benzenedicarboxylic acid
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DescriptionNS-3763 is a selective non-competitive kainate receptor antagonist. It displays selectivity for GLUK5 subunit-containing receptors (IC₅₀ values are 1.6 and > 30 mM for homomeric GLUK5 and GLUK6 receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC₅₀ > 30 μM).
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CAS Number70553-45-6
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Structure AvailableYes
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Molecular FormulaC₂₂H₁₆N₂O₆
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Molecular Weight404.38
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO ( ~10 mg/ml)
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HandlingProtect from air and light
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Tag LineA selective non-competitive kainate receptor antagonist
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00334657
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PubChem CID4359312
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SMILESC1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2C(=O)O)C(=O)O)NC(=O)C3=CC=CC=C3
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InChiInChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
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InChi KeyUUDYZUDTQPLDDP-UHFFFAOYSA-
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MSDS AvailableYes
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Gene target
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Gene symbolGNL3, IVNS1ABP, SPINK5
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Short nameNS-3763
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Alternative nameNS-3763
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Gene info
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Identity
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Gene
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Long gene nameG protein nucleolar 3
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Synonyms gene name
- guanine nucleotide binding protein-like 3 (nucleolar)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-01-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinfluenza virus NS1A binding protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-05-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BTB domain containing
- Kelch like
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameserine peptidase inhibitor Kazal type 5
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Synonyms gene name
- serine protease inhibitor, Kazal type 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-03-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serine peptidase inhibitors, Kazal type
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VEGA ID
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Locus Specific Databases