anti-Chk2 (Ab 516) Antibody

• Catalog number
  79-549
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cellular response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation
• Gene names
  CDS1, CHK2, LFS2, RAD53, hCds1, HuCds1, PP1425, NFKB3, CHEK2
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous levels of total Chk2 protein.
• Antigen
  Chk2 (Ab-516) antibody was made against a peptide sequence around aa. 514~518 (Q-P-S-T-S) derived from Chk2.
• Immuno application
  Western Blot
• Antibody advice
  Western Blot: 1:500~1:1000
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human
• Omim nr
  54112407
• Ncbi nr
  NP_001005735.1
• KDa
  62 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  11200
• GENE symbol
  CHEK2
• Antigene name
  checkpoint kinase 2
• Source
  This antibody was raised against a peptide sequence around aa. 514~518 (Q-P-S-T-S) derived from Chk2
• Protein nr
  O96017
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Chk2   516  
• Short name
  anti-Chk2 (Ab 516) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toChk2 (Antibody 516) (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products