TLR2 Antibody, Biotin Conjugated

• Catalog number
  bs-10472R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  TLR2 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TLR2
• Specificity
  This is a highly specific antibody against TLR2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  320-360/784
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human TLR2
• Gene ID number
  7097
• Swiss Prot
  O60603
• Tested applications
  WB, ELISA
• Recommended dilutions
  WB(1:100-1000), ELISA(1:500-1000)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  TIL4; CD282; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; TLR2
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  TLR2   Conjugated  
• Gene symbol
  TLR2
• Short name
  Anti-TLR2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-TLR2 PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 2, CD282 and TIL4, TLR2 and IDBG-41789 and ENSG00000137462 and 7097, lipopeptide binding, Cell surfaces, Tlr2 and IDBG-154818 and ENSMUSG00000027995 and 24088, TLR2 and IDBG-629032 and ENSBTAG00000008008 and 281534

Gene info

• Identity
  HGNC:11848
• Gene
  TLR2
• Long gene name
  toll like receptor 2
• Synonyms gene name
  • toll-like receptor 2
• Synonyms
  • TIL4
  • CD282
• GenBank acession
  • U88878
• Locus
  4q31.3
• Discovery year
  1998-06-25
• Entrez gene record
  7097
• Pubmed identfication
  • 9435236
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000161525

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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