anti- BTK antibody

• Catalog number
  FNab00980
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Immunogen
  Bruton agammaglobulinemia tyrosine kinase
• Synonyms
  AGMX1, ATK, BPK
• Calculated MW
  Refer to Figures
• Uniprot ID
  Q06187
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BTK  
• Gene symbol
  BTK
• Short name
  anti- BTK antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- Bruton agammaglobulinemia tyrosine kinase (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  Bruton agammaglobulinemia tyrosine kinase, AGMX1 and AT and ATK and BPK and IMD1 and PSCTK1 and XLA, BTK and IDBG-79651 and ENSG00000010671 and 695, phosphatidylinositol-3, nuclei, Btk and IDBG-171427 and ENSMUSG00000031264 and 12229, BTK and IDBG-633447 and ENSBTAG00000019250 and 533459

Gene info

• Identity
  HGNC:1133
• Gene
  BTK
• Long gene name
  Bruton tyrosine kinase
• Synonyms gene
  • AGMX1
  • IMD1
• Synonyms gene name
  • Bruton agammaglobulinemia tyrosine kinase
• Synonyms
  • ATK
  • XLA
  • PSCTK1
• Synonyms name
  • Bruton's tyrosine kinase
• GenBank acession
  • AK057105
• Locus
  Xq22.1
• Discovery year
  1986-01-01
• Entrez gene record
  695
• Pubmed identfication
  • 8380905
• RefSeq identity
  • NM_000061
• Classification
  • Tec family tyrosine kinases
  • SH2 domain containing
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000022022
• Locus Specific Databases
  • BTK base: Mutation registry for X-linked agammaglobulinemia
  • Global Variome shared LOVD
  • LRG_128

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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