8-Br-cGMP

• Catalog number
  1838-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  8- Bromoguanosine- 3', 5'- cyclic monophosphate, cyclic 8- bromoguanosine- 3', 5'- monophosphate, 8- bromoguanosine- 3', 5'-monophosphate
• Description
  A cell-permeable cGMP analog having greater resistance to hydrolysis by phosphodiesterases than cGMP. Activates cGMP-dependent protein kinase (PKG), slows or inhibits the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine. It inhibits thrombin stimulated arachidonic acid release in human platelets.
• CAS Number
  51116-01-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₀H₁₀BrN₅O₇P. Na
• Molecular Weight
  446.08
• Cell Permeable
  Yes
• Purity
  ≥95% by TLC
• Solubilities
  H₂O (~25 mg/ml) or aqueous buffers
• Handling
  Protect from moisture and light
• Tag Line
  A PKG activator
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00070128
• PubChem CID
  44134592
• PubChem CID Link
• SMILES
  C1C2C(C(C(O2)N3C4=C(C(=O)N=C(N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+]
• InChi
  InChI=1S/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5- 2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15, 18);/q;+1/p-1
• InChi Key
  ZJRFCXHKYQVNFK-UHFFFAOYSA-M
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  8-Br-cGMP  
• Short name
  8-Br-cGMP
• Alternative name
  8-Br-cGMP

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