p53 and MDM2 proteins-interaction-inhibitor (chiral)

• Catalog number
  HY-70027
• Price
  Please ask
• Size
  10mM/1mL

• Alternative_Names
  p53 inhibitor (chiral)
• CAS
  939981-37-0
• MWt
  734.75
• Formula
  C40H49Cl2N5O4
• Solubility
  10 mM in DMSO
• Clinical_Information
  No Development Reported
• Pathway
  Apoptosis
• Target
  MDM-2/p53
• Datasheet
• SDS
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  p53   MDM2   proteins-interaction-inhibitor   chiral  
• Gene symbol
  MDM2
• Short name
  p53 MDM2 proteins-interaction-inhibitor (chiral)
• Alternative name
  p53 and MDM2 proteins-interaction-suppressor (chiral)

Gene info

• Identity
  HGNC:6973
• Gene
  MDM2
• Long gene name
  MDM2 proto-oncogene
• Synonyms gene name
  • mouse double minute 2, human homolog of; p53-binding protein
  • Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)
  • Mdm2 p53 binding protein homolog (mouse)
  • MDM2 proto-oncogene, E3 ubiquitin protein ligase
• Synonyms
  • HDM2
  • MGC5370
• Locus
  12q15
• Discovery year
  1993-12-10
• Entrez gene record
  4193
• Pubmed identfication
  • 1614537
  • 16905769
  • 29123033
• RefSeq identity
  • NM_002392
• Classification
  • Zinc fingers RANBP2-type
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000142827

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