Rotenone

• Catalog number
  2248-250
• Price
  Please ask
• Size
  250 mg

• Alternative_name
  (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-][1]benzopyran-6(6aH)-one
• Description
  A broad spectrum insecticide that is cell-permeable and brain-permeable. Acts as a mitochondrial electron transport chain inhibitor (IC₅₀ = 1.7 - 2.2 μM at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC₅₀ = 3.4 nM). Neurotoxic agent that has also been used successfully to reproduce Parkinsons-like characteristics in in-vitro slice culture models.
• CAS Number
  83-79-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₂O₆
• Molecular Weight
  394.42
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  DMSO (100 mM) or EtOH (5 mM)
• Handling
  Protect from light and moisture
• Tag Line
  A mitochondrial electron transport chain inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD09025614
• PubChem CID
  6758
• PubChem CID Link
• SMILES
  CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC
• InChi
  InChI=1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1
• InChi Key
  JUVIOZPCNVVQFO-HBGVWJBISA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Rotenone  
• Short name
  Rotenone
• Alternative name
  Rotenone

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