Type
Conjugated Primary Antibody
Conjugated with
ALEXA FLUOR® 594
Host organism
Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide
ABCA9
Specificity
This antibody reacts specifically with ABCA9
Modification
No modification has been applied to this antibody
Modification site
None
Clonality
Polyclonal Antibody
Clone
Polyclonal Antibodies
Concentration
1ug per 1ul
Subcellular locations
N/A
Antigen Source
KLH conjugated synthetic peptide derived from human ABCA9
Gene ID
10350
Swiss Prot
N/A
Applications
IF(IHC-P)
Applications with corresponding dilutions
IF(IHC-P)(1:50-200)
Cross reactive species
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details
No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information
ABCA9 is a member of the superfamily of ATP-binding cassette (ABC) transporters and contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA9 is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of the ABCA9 gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. ABCA9 May play a role in monocyte differentiation and lipid homeostasis.
Purification method
Purified by Protein A.
Storage
Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission
590nm/617nm
Synonyms
ATP binding cassette A9; ATP binding cassette sub family A ABC1 member 9; ATP binding cassette sub family A member 9; DKFZp686F2450; EST640918; MGC75415; ABCA9_HUMAN.
Also known as
ABCA9 Polyclonal Antibody
Other name
Anti-ABCA9 Polyclonal
Advisory
Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties
For facs or microscopy Alexa 1 conjugate.
Conjugation
Alexa Fluor,ALEXA FLUOR® 594
Conjugated
Alexa conjugate 1
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group
Polyclonals and antibodies
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
