MOUSE Anti-HUMAN C4BP Antibody

  • Catalog number
    GEN212914
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    C4BP
  • Other names
    C4b-binding protein alpha chain; C4b-binding protein alpha chain; C4b-binding protein alpha chain; proline-rich protein; complement component 4 binding protein, alpha; Proline-rich protein
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    C4BP
  • Gene name synonims
    N/A
  • Other gene names
    C4BPA; C4BPA; PRP; C4BP; C4BP; C4bp; PRP
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2b
  • Clone
    42284
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    C4BP This item recognises complement component 4 binding protein (C4bp). There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. _x000D__x000D_C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. _x000D__x000D_Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    N/A
  • Form Appearance
    Purified (Purified IgG - liquid)
  • Concentration
    IgG concentration 1.0 mg/ml
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from the date of dispatch.
  • Tested applications
    ELISA (EIA)
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Test
    MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
    C4BP  
  • Gene symbol
    C4BPA, C4BPB
  • Short name
    MOUSE Anti- C4BP Antibody
  • Technique
    anti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
  • Host
    mouse
  • Species
    Human, Humans, Mouses
  • Alternative name
    Anti-MOUSE ANTI HUMAN C4BP
  • Alternative technique
    antibodies, murine
Gene info
  • Identity
  • Gene
  • Long gene name
    complement component 4 binding protein alpha
  • Synonyms gene
  • Synonyms gene name
    • complement component 4-binding protein, alpha
  • GenBank acession
  • Locus
  • Discovery year
    1986-01-01
  • Entrez gene record
    722
  • Classification
    • Complement system regulators and receptors
    • Sushi domain containing
  • VEGA ID
  • Locus Specific Databases
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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