Berberine Chloride
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Catalog number1830-100
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PricePlease ask
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Size100 mg
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Alternative_nameNatural Yellow 18, 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
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DescriptionAn isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic leukemia (ALL) cells with both MDM2 overexpression and a wild-type (wt)-p53, whereas no pro-apoptotic effect was detected in ALL cells that were negative for MDM2 and wt-p53.
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CAS Number633-65-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₀H₁₈ClNO₄
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Molecular Weight371.81
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Cell PermeableYes
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Purity≥98% by TLC
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SolubilitiesMeOH (50 mg/ml) or Water (~ 2 mg/ml)
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HandlingProtect from air and light
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Tag LineAn anticancer agent
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD00011939
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PubChem CID12456
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SMILESCOC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]
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InChiInChI=1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
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InChi KeyVKJGBAJNNALVAV-UHFFFAOYSA-M
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MSDS AvailableYes
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Gene target
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Short nameBerberine Chloride
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Alternative nameBerberine Chloride
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