sRANK Ligand, murine recombinant
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Catalog number4557-1000
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PricePlease ask
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Size1 mg
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SynonymsSoluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.
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Alternative_namesSoluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.
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DescriptionAn osteoclast differentiation and activation factor
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Purity≥98%
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Biological activityMeasured by its ability to induce osteoclast formation in RAW264.7 cells using a concentration of 5-10 ng/ml.
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Results5-10 ng/ml
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Molecular Weight19.4 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionLyophilized from 5 mM Tris, pH 7.6 + 75 mM NaCl
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Reconstitution InstructionsReconstitute in H₂O to a concentration of 0.1-1.0 mg /ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
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Background InformationMurine RANK (receptor activator of NF-kB) is a newly discovered member of the TNFR family, identified as a dendritic cell membrane protein. The recombinant murine sRANK Ligand is a soluble 19.4 kDa protein, comprising the 174 amino acid residue TNF homologous region of RANKL.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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Additional descriptionFAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Short namesRANK Ligand, murine recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative namesRANK Ligand, murine Rec.
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Alternative techniquerec
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MeSH Data
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Name
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ConceptScope note: Methods or procedures used to obtain samples of URINE.
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Tree numbers
- E01.370.225.998.762
- E05.200.998.762
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Qualifiersethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data