SRPIN340

• Catalog number
  2458-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]isonicotinamide; SRPK Inhibitor
• Description
  An ATP-competitive, serine/arginine-rich protein kinase (SRPK)-specific inhibitor (Ki = 0.89 µM for SRPK1). SRPIN 340 does not inhibit other classes of Serine-Arginine-Rich Protein Kinases (SRPKs) significantly, including Clk1 and Clk4 and >140 other SR kinases. SRPIN340 also suppresses VEGF expression and attenuates choroidal neovascularization (CNV).
• CAS Number
  218156-96-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₈F₃N₃O
• Molecular Weight
  349.35
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~100 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A SRPK inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• SMILES
  O=C(C1=CC=NC=C1)NC2=CC(C(F)(F)F)=CC=C2N3CCCCC3
• InChi
  InChI=1S/C18H18F3N3O/c19-18(20,21)14-4-5-16(24-10-2-1-3-11-24)15(12-14)23-17(25)13-6-8-22-9-7-13/h4-9,12H,1-3,10-11H2,(H,23,25)
• InChi Key
  DWFGGOFPIISJIT-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  SRPIN340  
• Short name
  SRPIN340
• Alternative name
  SRPIN340

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