Oridonin
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Catalog number1730-5
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PricePlease ask
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Size5 mg
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Alternative_nameNSC-250682
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DescriptionOridonin, a diterpenoid isolated from Rabdosia rubescens displays anti-inflammatory, anti-bacterial, anti-tumor effects and has been used for the treatment of human cancers, especially esophageal carcinoma. Exposure to oridonin induces apoptosis in AE (AML1-ETO)-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188
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CAS Number28957-04-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₀H₂₈N₅O₆
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Molecular Weight364.43
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Cell PermeableYes
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Purity≥97% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and moisture
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Tag LineA diterpenoid
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD00221762
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PubChem CID457846
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SMILESCC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C
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InChiInChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11, 14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10?,11?,12-,13+,15-,16-,18?,19?,20+/m0/s1
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InChi KeySDHTXBWLVGWJFT-ATGZISJRSA-N
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MSDS AvailableYes
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Gene target
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Short nameOridonin
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Alternative nameOridonin
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