ERCC1 (DNA excision repair protein), Antigen Immunoaffinity Purified Polyclonal

• Catalog number
  X2734P
• Price
  Please ask
• Size
  100µg

• Host Source
  Rabbit
• Clone Name
  NA
• Product Category
  Signal Transduction
• Species Reactivity
  Human
• Application
  Western Blot, Immunohistochemistry (paraffin-embedded)
• Immunogen
  Synthetic peptide derived from human ERCC1 protein
• Purification Method
  Antigen Immunoaffinity Purification
• Shipping Conditions
  Ship at ambient temperature, freeze upon arrival
• Storage conditions
  ERCC1 (DNA excision repair protein), Antigen Immunoaffinity Purified Polyclonal should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
• Datasheet link
• Description
  Antigens are peptides or recombinant or native dependent on the production method.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  ERCC1   DNA   excision   repair   protein   Immunoaffinity  
• Gene symbol
  ERCC1, PRKDC, HLA-DOA
• Short name
  ERCC1 (DNA excision repair protein), Antigen Immunoaffinity Purified Polyclonal
• Technique
  Polyclonal, purified, antigen, dna, antigenes, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope. purifications
• Isotype
  Ig
• Alternative name
  excision repair cross-complementing rodent repair deficiency, complementation family 1 (includes overlapping antisense sequence) (Desoxyribonucleic acid excision repair protein), protein Immunoaffinity enriched polyclonal
• Alternative technique
  polyclonals, pure, antigenes
• Alternative to gene target
  excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), COFS4 and RAD10 and UV20, ERCC1 and IDBG-57509 and ENSG00000012061 and 2067, structure-specific DNA binding, nuclei, Ercc1 and IDBG-150201 and ENSMUSG00000003549 and 13870, ERCC1 and IDBG-639466 and ENSBTAG00000017355 and 615637

Gene info

• Identity
  HGNC:3433
• Gene
  ERCC1
• Long gene name
  ERCC excision repair 1, endonuclease non-catalytic subunit
• Synonyms gene name
  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
  • excision repair cross-complementation group 1
• Synonyms
  • RAD10
• Locus
  19q13.32
• Discovery year
  2001-06-22
• Entrez gene record
  2067
• Pubmed identfication
  • 6462228
  • 26939044
• RefSeq identity
  • NM_001983
• Classification
  • ERCC excision repair associated
• VEGA ID
  OTTHUMG00000182121
• Locus Specific Databases
  • LRG_305

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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