Cyclopamine-KAAD

• Catalog number
  1910-50
• Price
  Please ask
• Size
  50 ug

• Alternative_name
  3-Keto-N-(aminoethyl-N’-aminocaproyldihydrocinnamoyl)cyclopamine; KAAD-cyclopamine
• Description
  Cell-permeable. A synthetic derivative of the natural product Cyclopamine (Cat. No. 1578-5) that acts as a specific inhibitor of Smoothened (Smo) and Sonic hedgehog (Shh) intracellular signaling (IC₅₀ = 20 nM in the Shh-LIGHT2 assay).
• CAS Number
  306387-90-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₄₄H₆₃N₃O₄
• Molecular Weight
  697.99
• Cell Permeable
  Yes
• Purity
  ≥80% by HPLC
• Solubilities
  DMSO or EtOH
• Handling
  Protect from air and moisture
• Tag Line
  A Smoothened (Smo) antagonist
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD03425585
• PubChem CID
  16760383
• PubChem CID Link
• SMILES
  CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(=O)CCC6(C5CC4=C3C)C)C)N(C1)CCNC(=O)CCCCCNC (=O)CCC7=CC=CC=C7
• InChi
  InChI=1S/C44H63N3O4/c1-29-25-39-42(47(28-29)24-23-46-40(49)13-9-6-10-22- 45-41(50)17-14-32-11-7-5-8-12-32)31(3)44(51-39)21-19-35-36-16-15-33-26- 34(48)18-20-43(33,4)38(36)27-37(35)30(44)2/h5,7-8,11-12,15,29,31,35-36, 38-39,42H,6,9-10,13-14,16-28H2,1-4H3,(H,45,50)(H,46,49)/t29?,31-,35?, 36?,38?,39-,42?,43?,44?/m1/s1
• InChi Key
  WDHRPWOAMDJICD-BWBMXWGBSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Cyclopamine-KAAD  
• Short name
  Cyclopamine-KAAD
• Alternative name
  Cyclopamine-KAAD

Product images

Similar products