Factor XIa Activity Assay Kit (Colorimetric)

• Catalog number
  K973-100
• Price
  Please ask
• Size
  100 assays

• Description
  Highly Sensitive, minimum sample preparation required
• Summary
  • Detection method- Colorimetric (Absorbance 405 nm) • Applications- Measurement of FXIa activity in plasma and purified/crude enzyme preparations
• Detection Method
  Colorimetric (Absorbance 405 nm)
• Species Reactivity
  Mammalians
• Applications
  Measurement of Factor XIIIa activity in plasma samples and purified/crude enzyme preparations
• Sample Type
  • Plasma • Purified enzyme
• Features Benefits
  • Simple, rapid & convenient assay to measure Factor XIa • Includes Positive Control and Factor Xia and Factor XIIa Inhibitors
• Storage Conditions
  -20°C
• Shipping Conditions
  gel pack
• Shelf life
  12 months
• Background
  Factor XI or plasma thromboplastin antecedent (EC 3.4.21.27), the zymogen form of factor XIa, is a serine protease. In humans, Factor XI is encoded by the F11 gene. Factor XI (FXI) circulates as a homo-dimer in its inactive form activated into factor XIa by factor XIIa (FXIIa) via the "contact pathway", thrombin, and self-activation by its active form (FXIa). The deficiency of factor XI causes the rare hemophilia C which is an autosomal recessive disorder characterized by lower spontaneous bleeding, but excessive blood loss during surgical procedures. Low levels of factor XI also occur in many other disease states, including Noonan syndrome. High levels of factor XI have been implicated in thrombosis. Factor XIa also activates factor IX which, in turn, activates factor X in the coagulation cascade. BioVision's Factor XIa activity assay kit utilizes the ability of factor XIa to cleave a synthetic substrate to release p-Nitroaniline (pNA) which can be quantitatively measured by a colorimetric assay (OD 405 nm). The kit is easy-to-use and can detect Factor XIa (as low as 1 mPEU) from plasma and purified protein samples.
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.
• Properties
  Colorimetric assays or detection use UV absorption or enzymatic color reaction.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

• Gene target
  Factor   XIa   Activity   Kit  
• Short name
  Factor XIa Activity Assay Kit (Colorimetric)
• Technique
  colorimetric, Assay, assays, colorimetry
• Host
  Assay
• Alternative name
  Factor XIa Activity test reagent (colorimetry)
• Alternative technique
  assays, arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

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