DNA PKcs Antibody (pThr2609) : FITC

• Catalog number
  SPC-1368D-FITC
• Price
  Please ask
• Size
  100 µl

• Target
  DNA PKcs (pThr2609) 
• Conjugate
  FITC
• Research Area s
  Cell Signaling, Epigenetics and Nuclear Signaling, DNA/RNA, DNA Damage and Repair, Non Homologous End Joining, Cell Signaling, Epigenetics and Nuclear Signaling, DNA/RNA, DNA Damage and Repair, DNA Damage Recognition
• Alternative Name s
  DNA PK Antibody, DNA-PK Antibody, DNA-PK catalytic subunit Antibody, HYRC 1 Antibody, Protein Kinase DNA Activated Catalytic Polypeptide Antibody, p460 Antibody, p350 Antibody, HYRC Antibody, EC:2.7.11.1 Antibody, XRCC 7 Antibody, DNPK1 Antibody, PRKDC Antibody, DNA-PKcs Antibody, DNAPK Antibody, Hyper radiosensitivity of murine scid mutation, complementing 1 Antibody, DNA dependent protein kinase catalytic subunit Antibody, HYRC1 Antibody, XRCC7 Antibody, IMD26 Antibody, DNAPK catalytic subunit Antibody, PKRDC Antibody, DNPK 1 Antibody, PRKDC_HUMAN Antibody, Hyperradiosensitivity complementing 1, mouse, homolog of 1 Antibody, DNA-dependent protein kinase catalytic subunit Antibody, DNA PK catalytic subunit Antibody
• Category
  Antibodies
• Product Type
  Polyclonal
• Immunogen
  Synthetic phospho-peptide from human DNA PKcs around the phosphorylation site threonine 2609 (pThr2609) .
• Immunogen Species
  Human
• Accession Number
  NP_001075109.1
• Gene ID
  5591
• Swiss Prot
  P78527
• Applications
  WB
• Host Species
  Rabbit
• Species Reactivity
  Human
• Antibody Dilution
  WB (1:500-1500); optimal dilutions for assays should be determined by the user.
• Purification
  Peptide Affinity Purified
• Storage Buffer
  PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
• Specificity
  Detects endogenous levels of DNA PKcs only when phosphorylated at threonine 2609 (pThr2609) . Detects a band at ~450 kDa.
• Storage Temperature
  -20ºC
• Shipping Temperature
  Blue Ice or 4ºC
• Cellular Localization
  Nucleus, Nucleolus, Cytosol, Extracellular Matrix, DNA-Dependent Protein Kinase-DNA Ligase 4 Complex, Nuclear Chromosome Telomeric Region, Nucleoplasm, Membrane, Nonhomologous End Joining Complex, Protein Complex
• Field of Use
  For in vitro research use only.
• Technical data
• SDS
• Gross Weight kg
  1.4
• Net Weight g
  0.1
• Properties
  If you buy Antibodies supplied by StressMarq they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This StressMarq Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. StressMarq FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  DNA   PKcs   pThr2609  
• Gene symbol
  PRKDC, HLA-DOA
• Short name
  DNA PKcs Antibody (pThr2609) : FITC
• Technique
  Antibody, FITC, dna, antibodies against human proteins, antibodies for, Fluorescein
• Isotype
  IgG
• Label
  FITC
• Alternative name
  Desoxyribonucleic acid PKcs (antibody to-) (pThr2609) : fluorecein
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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