MOUSE Anti-HUMAN BETA AMYLOID (aa37-42) Antibody

• Catalog number
  GEN224661
• Price
  Please ask
• Size
  100ug

• Also known as
  BETA AMYLOID
• Other names
  amyloid beta A4 protein isoform a; Amyloid beta A4 protein; amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; amyloid beta (A4) precursor protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-IICleaved into the following 14 chains:N-APPSoluble APP-alpha; S-APP-alphaSoluble APP-beta; S-APP-betaC99Beta-amyloid protein 42; Alternative name(s):; Beta-APP42Beta-amyloid protein 40; Alternative name(s):; Beta-APP40C83P3(42)P3(40)C80Gamma-secretase C-terminal fragment 59; Alternative name(s):; Amyloid intracellular domain 59; AICD-59; AID(59); Gamma-CTF(59)Gamma-secretase C-terminal fragment 57; Alternative name(s):; Amyloid intracellular domain 57; AICD-57; AID(57); Gamma-CTF(57)Gamma-secretase C-terminal fragment 50; Alternative name(s):; Amyloid intracellular domain 50; AICD-50; AID(50); Gamma-CTF(50)
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  BETA AMYLOID
• Gene name synonims
  N/A
• Other gene names
  APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  MAb1.1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  BETA AMYLOID Clone Mab1.1 recognises Beta-amyloid protein 42 (also known as Aβ42), the 42 amino acid peptide processed from Amyloid precursor protein (APP). There are several forms of Aβ peptides processed from APP, the most common being Aβ40 and Aβ42. Amyloid plaques contain both Aβ40 and Aβ42. Aβ40 is more common, but Aβ42 more fibrillogenic and therefore associated with disease states such as Alzheimer's disease. Clone Mab1.1 specifically binds to the 37-42aa region, and does not recognise full-length APP or the 40 amino acid peptide processed from APP (Aβ40). It stains diffuse plaques found in the brain of Alzheimer's disease patients. It does not stain healthy brain tissue or other organs.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Purified (Purified IgG - liquid)
• Concentration
  IgG concentration 1.0 mg/ml
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
• Tested applications
  Immunohistology - Paraffin (IHC), Immunohistology - Frozen (IHC), ELISA (EIA)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  BETA   AMYLOID   aa37-42  
• Gene symbol
  KCNMB1, NAPB, DNAJC5B, GPR63, CBX1, CGB7, AGPAT2, EDDM3B, TLK1, HSD17B11
• Short name
  MOUSE Anti- BETA AMYLOID (aa37-42) Antibody
• Technique
  anti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
• Host
  mouse
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-MOUSE ANTI HUMAN BETA AMYLOID (aa37-42)
• Alternative technique
  antibodies, murine

Gene info

• Identity
  HGNC:6285
• Gene
  KCNMB1
• Long gene name
  potassium calcium-activated channel subfamily M regulatory beta subunit 1
• Synonyms gene name
  • potassium large conductance calcium-activated channel, subfamily M, beta member 1
  • potassium channel subfamily M regulatory beta subunit 1
• Synonyms
  • hslo-beta
• Synonyms name
  • BK channel beta subunit 1
  • MaxiK channel beta-subunit 1
  • big potassium channel beta subunit 1
• GenBank acession
  • AF035046
• Locus
  5q35.1
• Discovery year
  1997-12-05
• Entrez gene record
  3779
• Pubmed identfication
  • 8799178
  • 9888999
• Classification
  • Potassium calcium-activated channel subfamily M regulatory beta subunits
• VEGA ID
  OTTHUMG00000130439

Gene info

• Identity
  HGNC:15751
• Gene
  NAPB
• Long gene name
  NSF attachment protein beta
• Synonyms gene name
  • N-ethylmaleimide-sensitive factor attachment protein, beta
• Synonyms
  • SNAP-BETA
  • SNAPB
• Synonyms name
  • beta soluble NSF attachment protein
• GenBank acession
  • AK022817
• Locus
  20p11.21
• Discovery year
  2001-05-30
• Entrez gene record
  63908
• Pubmed identfication
  • 8455721
• RefSeq identity
  • NM_022080
• VEGA ID
  OTTHUMG00000032062

Gene info

• Identity
  HGNC:24138
• Gene
  DNAJC5B
• Long gene name
  DnaJ heat shock protein family (Hsp40) member C5 beta
• Synonyms gene name
  • DnaJ (Hsp40) homolog, subfamily C, member 5 beta
• Synonyms
  • MGC26226
  • CSP-beta
• GenBank acession
  • AF368276
• Locus
  8q13.1
• Discovery year
  2004-03-16
• Entrez gene record
  85479
• Pubmed identfication
  • 29182667
• RefSeq identity
  • NM_033105
• Classification
  • DNAJ (HSP40) heat shock proteins
• VEGA ID
  OTTHUMG00000164470

Gene info

• Identity
  HGNC:13302
• Gene
  GPR63
• Long gene name
  G protein-coupled receptor 63
• Synonyms
  • PSP24(beta)
  • PSP24B
• GenBank acession
  • AF317654
• Locus
  6q16.1
• Discovery year
  2001-04-05
• Entrez gene record
  81491
• Classification
  • G protein-coupled receptors, Class A orphans
• VEGA ID
  OTTHUMG00000015245

Gene info

• Identity
  HGNC:1551
• Gene
  CBX1
• Long gene name
  chromobox 1
• Synonyms gene name
  • chromobox homolog 1 (Drosophila HP1 beta)
  • chromobox homolog 1
• Synonyms
  • HP1Hs-beta
  • M31
  • MOD1
  • CBX
  • HP1-BETA
• Synonyms name
  • HP1 beta homolog (Drosophila )
• GenBank acession
  • U35451
• Locus
  17q21.32
• Discovery year
  1999-10-12
• Entrez gene record
  10951
• Pubmed identfication
  • 9169582
• RefSeq identity
  • NM_006807
• Classification
  • Chromobox family
• VEGA ID
  OTTHUMG00000150417

Gene info

• Identity
  HGNC:16451
• Gene
  CGB7
• Long gene name
  chorionic gonadotropin subunit beta 7
• Synonyms gene name
  • chorionic gonadotropin, beta polypeptide 7
  • chorionic gonadotropin beta subunit 7
• Synonyms
  • CG-beta-a
• GenBank acession
  • K00092
• Locus
  19q13.33
• Discovery year
  2001-12-05
• Entrez gene record
  94027
• Pubmed identfication
  • 6194155
• RefSeq identity
  • NM_033142
• Classification
  • Glycoprotein hormone subunits
• VEGA ID
  OTTHUMG00000183339

Gene info

• Identity
  HGNC:325
• Gene
  AGPAT2
• Long gene name
  1-acylglycerol-3-phosphate O-acyltransferase 2
• Synonyms gene
  • BSCL
• Synonyms gene name
  • Berardinelli-Seip congenital lipodystrophy
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
• Synonyms
  • LPAAT-beta
• Synonyms name
  • lysophosphatidic acid acyltransferase-beta
• GenBank acession
  • AF000237
• Locus
  9q34.3
• Discovery year
  1999-12-07
• Entrez gene record
  10555
• Pubmed identfication
  • 9242711
  • 9212163
• RefSeq identity
  • NM_006412
• Classification
  • 1-acylglycerol-3-phosphate O-acyltransferases
• VEGA ID
  OTTHUMG00000020936

Gene info

• Identity
  HGNC:19223
• Gene
  EDDM3B
• Long gene name
  epididymal protein 3B
• Synonyms gene
  • FAM12B
• Synonyms gene name
  • family with sequence similarity 12, member B (epididymal)
• Synonyms
  • HE3-BETA
• GenBank acession
  • X76386
• Locus
  14q11.2
• Discovery year
  2002-09-23
• Entrez gene record
  64184
• Pubmed identfication
  • 7514008
• VEGA ID
  OTTHUMG00000029583

Gene info

• Identity
  HGNC:11841
• Gene
  TLK1
• Long gene name
  tousled like kinase 1
• Synonyms gene name
  • tousled-like kinase 1
• Synonyms
  • KIAA0137
  • PKU-BETA
• GenBank acession
  • AB004885
• Locus
  2q31.1
• Discovery year
  2000-01-07
• Entrez gene record
  9874
• Pubmed identfication
  • 9427565
  • 12660173
• RefSeq identity
  • NM_012290
• VEGA ID
  OTTHUMG00000132243

Gene info

• Identity
  HGNC:22960
• Gene
  HSD17B11
• Long gene name
  hydroxysteroid 17-beta dehydrogenase 11
• Synonyms gene
  • DHRS8
• Synonyms gene name
  • dehydrogenase/reductase (SDR family) member 8
  • hydroxysteroid (17-beta) dehydrogenase 11
• Synonyms
  • RetSDR2
  • 17-BETA-HSD11
  • 17-BETA-HSDXI
  • PAN1B
  • SDR16C2
• Synonyms name
  • retinal short-chain dehydrogenase/reductase 2
  • short chain dehydrogenase/reductase family 16C, member 2
• GenBank acession
  • AF126780
• Locus
  4q22.1
• Discovery year
  2003-12-02
• Entrez gene record
  51170
• Pubmed identfication
  • 11165019
  • 12697717
  • 19027726
• RefSeq identity
  • NM_016245
• Classification
  • Short chain dehydrogenase/reductase superfamily
• VEGA ID
  OTTHUMG00000130594

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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