EphA2 Antibody, ALEXA FLUOR 555

• Catalog number
  bs-0485R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  EphA2 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-EphA2 PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  EphA2
• Specificity
  This is a highly specific antibody against EphA2.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  920-970/976
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EphA2
• Gene ID Number
  1969
• Swiss Prot
  P29317
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  ECK; CTPA; ARCC2; CTPP1; CTRCT6; Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK; EPHA2
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  EphA2  
• Gene symbol
  EPHA2-AS1, EPHA2
• Short name
  Anti-EphA2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  EphA2 Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies
• Alternative to gene target
  EPH receptor A2, ARCC2 and CTPA and CTPP1 and CTRCT6 and ECK, EPHA2 and IDBG-91407 and ENSG00000142627 and 1969, transferase activity, Cell surfaces, Epha2 and IDBG-202005 and ENSMUSG00000006445 and 13836, EPHA2 and IDBG-645870 and ENSBTAG00000000815 and 512798

Gene info

• Identity
  HGNC:40216
• Gene
  EPHA2-AS1
• Long gene name
  EPHA2 antisense RNA 1
• Locus
  1p36.13
• Discovery year
  2021-07-29
• Entrez gene record
  101927479
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3386
• Gene
  EPHA2
• Long gene name
  EPH receptor A2
• Synonyms gene
  • ECK
• Synonyms gene name
  • EphA2
• GenBank acession
  • BC037166
• Locus
  1p36.13
• Discovery year
  1991-08-07
• Entrez gene record
  1969
• Pubmed identfication
  • 9119409
• RefSeq identity
  • NM_004431
• Classification
  • Sterile alpha motif domain containing
  • EPH receptors
• VEGA ID
  OTTHUMG00000009527

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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