Anti-PD-L1 Antibody

• Catalog number
  A1454-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  PD-L1
• Target Alternative Name
  PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human PD-L1
• Accession
  Q9NZQ7
• Gene Id
  29126
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% Proclin
• Purification
  Affinity purified
• Application
  WB
• Positive Control
  WB: PD-L1 human recombinant
• Application And Usages
  WB: 1-4 µg
• Description
  Programmed death 1 ligand 1 (PD-L1) also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PD-L1  
• Gene symbol
  CD274, ENPP2, MTA2, MICALL1, IGKV1-16, ZBTB4, UCHL1, COLEC10, PDCD1, FAM71F1
• Short name
  Anti-PD-L1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toPD-L1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17635
• Gene
  CD274
• Long gene name
  CD274 molecule
• Synonyms gene
  • PDCD1LG1
• Synonyms gene name
  • programmed cell death 1 ligand 1
  • CD274 antigen
• Synonyms
  • B7-H
  • B7H1
  • PD-L1
  • PDL1
  • B7-H1
• Synonyms name
  • B7 homolog 1
• GenBank acession
  • AF177937
• Locus
  9p24.1
• Discovery year
  2003-11-13
• Entrez gene record
  29126
• Pubmed identfication
  • 11015443
  • 10581077
• RefSeq identity
  • NM_014143
• Classification
  • Receptor ligands
  • C2-set domain containing
  • V-set domain containing
  • B7 family
  • CD molecules
• VEGA ID
  OTTHUMG00000019503

Gene info

• Identity
  HGNC:3357
• Gene
  ENPP2
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 2
• Synonyms gene
  • PDNP2
• Synonyms
  • ATX
  • PD-IALPHA
• Synonyms name
  • autotaxin
• GenBank acession
  • D45421
• Locus
  8q24.12
• Discovery year
  1995-08-10
• Entrez gene record
  5168
• Pubmed identfication
  • 8586446
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
• VEGA ID
  OTTHUMG00000164995

Gene info

• Identity
  HGNC:7411
• Gene
  MTA2
• Long gene name
  metastasis associated 1 family member 2
• Synonyms gene
  • MTA1L1
• Synonyms gene name
  • metastasis associated gene family, member 2
• Synonyms
  • MTA1-L1
• GenBank acession
  • AB016591
• Locus
  11q12.3
• Discovery year
  1999-05-17
• Entrez gene record
  9219
• Pubmed identfication
  • 9929979
• RefSeq identity
  • NM_004739
• Classification
  • GATA zinc finger domain containing
  • NuRD complex subunits
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000167684

Gene info

• Identity
  HGNC:29804
• Gene
  MICALL1
• Long gene name
  MICAL like 1
• Synonyms gene name
  • MICAL-like 1
• Synonyms
  • MIRAB13
  • KIAA1668
  • MICAL-L1
• Synonyms name
  • molecule interacting with Rab13
• GenBank acession
  • BK000466
• Locus
  22q13.1
• Discovery year
  2006-11-24
• Entrez gene record
  85377
• Pubmed identfication
  • 11258795
  • 12110185
• RefSeq identity
  • NM_033386
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000150670

Gene info

• Identity
  HGNC:5732
• Gene
  IGKV1-16
• Long gene name
  immunoglobulin kappa variable 1-16
• Synonyms
  • IGKV116
  • L1
• GenBank acession
  • J00248
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28938
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151649

Gene info

• Identity
  HGNC:23847
• Gene
  ZBTB4
• Long gene name
  zinc finger and BTB domain containing 4
• Synonyms
  • KIAA1538
  • KAISO-L1
  • ZNF903
• GenBank acession
  • AB040971
• Locus
  17p13.1
• Discovery year
  2003-12-15
• Entrez gene record
  57659
• Pubmed identfication
  • 16354688
  • 25499219
• RefSeq identity
  • NM_020899
• Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000108137

Gene info

• Identity
  HGNC:12513
• Gene
  UCHL1
• Long gene name
  ubiquitin C-terminal hydrolase L1
• Synonyms gene
  • PARK5
• Synonyms gene name
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
• Synonyms
  • PGP9.5
  • Uch-L1
• Synonyms name
  • ubiquitin thiolesterase
• GenBank acession
  • BC000332
• Locus
  4p13
• Discovery year
  1991-07-15
• Entrez gene record
  7345
• Pubmed identfication
  • 1840236
• RefSeq identity
  • NM_004181
• Classification
  • Ubiquitin C-terminal hydrolases
• VEGA ID
  OTTHUMG00000099377

Gene info

• Identity
  HGNC:2220
• Gene
  COLEC10
• Long gene name
  collectin subfamily member 10
• Synonyms gene name
  • collectin sub-family member 10 (C-type lectin)
• Synonyms
  • CL-L1
  • CL-10
• GenBank acession
  • AB002631
• Locus
  8q24.12
• Discovery year
  2000-04-11
• Entrez gene record
  10584
• Pubmed identfication
  • 10224141
• Classification
  • Collectins
  • C-type lectin domain containing
  • Complement system activation components
• VEGA ID
  OTTHUMG00000164971

Gene info

• Identity
  HGNC:8760
• Gene
  PDCD1
• Long gene name
  programmed cell death 1
• Synonyms gene
  • SLEB2
• Synonyms gene name
  • systemic lupus erythematosus susceptibility 2
• Synonyms
  • CD279
  • PD1
  • hSLE1
  • PD-1
• GenBank acession
  • AY206416
• Locus
  2q37.3
• Discovery year
  1994-05-24
• Entrez gene record
  5133
• Pubmed identfication
  • 7851902
  • 12402038
• RefSeq identity
  • NM_005018
• Classification
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000151342

Gene info

• Identity
  HGNC:30704
• Gene
  FAM71F1
• Long gene name
  family with sequence similarity 71 member F1
• Synonyms gene
  • FAM137A
• Synonyms gene name
  • family with sequence similarity 137, member A
  • family with sequence similarity 71, member F1
• Synonyms
  • NYD-SP18
  • GARI-L1
• Synonyms name
  • Golgi-associated RAB2B interactor like 1
• GenBank acession
  • AF367470
• Locus
  7q32.1
• Discovery year
  2007-07-24
• Entrez gene record
  84691
• Pubmed identfication
  • 12477932
  • 34714330
• RefSeq identity
  • NM_032599
• VEGA ID
  OTTHUMG00000158276

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products