Present as an active principle in the plant Magnolia grandiflora. Displays anxiolytic, antithrombotic, anti-tumor properties, etc. modulates the NF-κB activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides.
2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol; HNK; Houpa
Is this a salt?
Is it cell-permeable?
≥97% by HPLC
DMSO (10 mg/ml) or EtOH
Maximum time for storage
Protect from air and moisture
For cells, cell lines and tissues in culture till half confluency.
Honokiol for activation
Honokiol to measure cellular activation