anti- MMP7 antibody

  • Catalog number
    FNab05245
  • Price
    Please ask
  • Size
    2X100μg
  • Form
    liquid
  • Purification
    Immunogen affinity purified
  • Purity
    ≥95% as determined by SDS-PAGE
  • Storage
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background
    This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.
  • Immunogen
    matrix metallopeptidase 7 (matrilysin, uterine)
  • Synonyms
    Matrilysin, Matrin, Matrix metalloproteinase 7, MMP 7, MMP7, MPSL1, PUMP 1, Pump 1 protease, PUMP1, Uterine metalloproteinase
  • Calculated MW
    30 kDa
  • Uniprot ID
    P09237
  • Specificity
    Human, Mouse, Rat
  • Tested Application
    ELISA, WB, IHC
  • Recommended dilution
    WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
  • Image1
    Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab05245(MMP7 antibody) at dilution of 1:100
  • Image4
    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab05245(MMP7 antibody) at dilution of 1:1000
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    MMP7  
  • Gene symbol
    MMP7
  • Short name
    anti- MMP7 antibody
  • Technique
    Antibody, anti, antibody to, antibodies against human proteins, antibodies for
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    antibody to- MMP7 (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    matrix metallopeptidase 7
  • Synonyms gene
  • Synonyms gene name
    • matrix metalloproteinase 7 (matrilysin, uterine)
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1991-07-15
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • M10 matrix metallopeptidases
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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