ZM 336372

• Catalog number
  1789-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
• Description
  Cell-permeable. A potent, selective and ATP-competitive inhibitor of c-Raf in vitro (IC₅₀ = 70 nM for inhibition of human c-Raf). Displays 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC₅₀= 2 μM).
• CAS Number
  208260-29-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₃N₃O₃
• Molecular Weight
  389.45
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (100 mM)
• Handling
  Protect from air and light
• Tag Line
  A c-Raf kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  48 months
• MDL Number
  MFCD02683971
• PubChem CID
  5730
• PubChem CID Link
• SMILES
  CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O
• InChi
  InChI=1S/C23H23N3O3/c1-15-7-10-18(24-23(29)17-5-4-6-19(13-17)26(2)3)14-21(15)25-22(28)16-8-11-20(27)12-9-16/h4-14,27H,1-3H3,(H,24,29)(H,25,28)
• InChi Key
  PYEFPDQFAZNXLI-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  336372  
• Short name
  ZM 336372
• Alternative name
  ZM 336372

Similar products